Soluble in water (<1 mg/ml) at 25 °C, DMSO (13 mg/ml) at 25 °C, and ethanol (<1 mg/ml) at 25 °C.
存貯條件
儲存溫度-20°C
描述
產品介紹
Y2603618是一種選擇性Chk1抑制劑,具有潛在的抗腫瘤活性。Phase 2。
用途
A selective Chk1 inhibitor.
生化機理
LY2603618 (IC-83) is a very selective checkpoint kinase 1 (Chk1) inhibitor with the potential for antitumor effects. Chk1 is an ATP-dependent serine-threonine kinase that is very important to the checkpoint monitoring system of DNA replication.